Caffeine shot delivers wakeup call on antifungal drug resistance

(University of Edinburgh) The management of fungal infections in plants and humans could be transformed by a breakthrough in understanding how fungi develop resistance to drugs. It was previously thought that only mutations in a fungi's DNA would result in antifungal drug resistance. Current diagnostic techniques rely on sequencing all of a fungi's DNA to find such mutations. Scientists from the University of Edinburgh have discovered that fungi can develop drug resistance without changes to the...